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Characteristics and Outcome of Children with Renal Cell Carcinoma: A Narrative Review

van der Beek, JN; Geller, JI; de Krijger, RR; Graf, N; Pritchard-Jones, K; Drost, J; Verschuur, AC; ... van den Heuvel-Eibrink, MM; + view all (2020) Characteristics and Outcome of Children with Renal Cell Carcinoma: A Narrative Review. Cancers , 12 (7) , Article 1776. 10.3390/cancers12071776. Green open access

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Abstract

Pediatric renal cell carcinoma (RCC) is a rare type of kidney cancer, most commonly occurring in teenagers and young adolescents. Few relatively large series of pediatric RCC have been reported. Knowledge of clinical characteristics, outcome and treatment strategies are often based on the more frequently occurring adult types of RCC. However, published pediatric data suggest that clinical, molecular and histological characteristics of pediatric RCC differ from adult RCC. This paper summarizes reported series consisting of ≥10 RCC pediatric patients in order to create an up-to-date overview of the clinical and histopathological characteristics, treatment and outcome of pediatric RCC patients.

Type: Article
Title: Characteristics and Outcome of Children with Renal Cell Carcinoma: A Narrative Review
Location: Switzerland
Open access status: An open access version is available from UCL Discovery
DOI: 10.3390/cancers12071776
Publisher version: http://dx.doi.org/10.3390/cancers12071776
Language: English
Additional information: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
Keywords: outcome, pediatric, renal cell carcinoma, survival, treatment
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Biology and Cancer Dept
URI: https://discovery.ucl.ac.uk/id/eprint/10105881
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