Stone, Sheldon Paul; (1994) The prognosis of the neglect syndrome in acute stroke. Doctoral thesis (M.D), UCL (University College London).

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Abstract

The natural history of the neglect syndrome after acute stroke is not clear. The main reasons for this are that different studies have examined patients at different times post-stroke, using different clinical tests without adequate control data, and often without strict definitions of the various neglect phenomena. The prognostic features in the recovery of patients presenting with visual neglect has been examined in only one study. The design of this study may have lead to under-detection of visual neglect and may have exaggerated the association of neglect with a poor outcome. In addition, by grouping all dependent patients together, irrespective of the degree of dependency, the study may have failed to target the group in greatest need of therapeutic intervention. This thesis aims to re-examine the incidence and speed of recovery of the various features of the neglect syndrome in patients with acute stroke. In particular, it seeks to determine the predictors of the severity of visual neglect and of the level of independence in survivors at 3 months and at 6 months. These predictors may be helpful in selecting patients for trials of treatment of visual neglect.

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