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Lipotransfer provides effective soft tissue replacement for acquired partial lipodystrophy

Jeon, FHK; Griffin, M; Frosdick, C; Butler, PEM; (2020) Lipotransfer provides effective soft tissue replacement for acquired partial lipodystrophy. BMJ Case Reports , 13 (5) , Article e232601. 10.1136/bcr-2019-232601. Green open access

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Abstract

We present a 48-year-old female patient who presented with features consistent with acquired partial lipodystrophy (APL) also known as 'Barraquer-Simons syndrome'. It is a rare disease characterised by a gradual and progressive onset of lipoatrophy limited to the face, neck, upper limbs, thorax and abdomen and sparing the lower extremities. The resultant physical appearance can have significant psychosocial sequelae, further compounded by misdiagnosis and delay in recognition and management. Treatment is aimed at surgical correction of soft tissue destruction. Autologous fat transfer is an established plastic and reconstructive procedure that is safe and minimally invasive and can be used to reconstruct a variety of soft tissue defects and has shown to be an effective treatment modality in patients with APL.

Type: Article
Title: Lipotransfer provides effective soft tissue replacement for acquired partial lipodystrophy
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1136/bcr-2019-232601
Publisher version: http://dx.doi.org/10.1136/bcr-2019-232601
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: breast surgery, plastic and reconstructive surgery
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Surgical Biotechnology
URI: https://discovery.ucl.ac.uk/id/eprint/10102937
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