Al-Araji, S;
Ciccarelli, O;
(2021)
A possible case of serum sickness after ocrelizumab infusion – Commentary.
Multiple Sclerosis Journal
, 27
(1)
pp. 158-159.
10.1177/1352458520923947.
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Abstract
Serum sickness is a type III delayed hypersensitivity reaction which causes deposition of immune-complexes in the tissues. It has been reported with rituximab, and in this issue of the journal, there is a case report of a patient with relapsing remitting multiple sclerosis who developed a possible serum sickness after the third infusion of ocrelizumab. In this commentary, we discuss the current literature on serum sickness, and how to diagnose and manage it. We provide our opinion on this particular case, and encourage neurologists and patients to remain vigilant of such a possibility.
Type: | Article |
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Title: | A possible case of serum sickness after ocrelizumab infusion – Commentary |
Open access status: | An open access version is available from UCL Discovery |
DOI: | 10.1177/1352458520923947 |
Publisher version: | https://doi.org/10.1177/1352458520923947 |
Language: | English |
Additional information: | This article is distributed under the terms of the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
Keywords: | Multiple sclerosis, ocrelizumab |
UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Neuroinflammation |
URI: | https://discovery.ucl.ac.uk/id/eprint/10102704 |
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