UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Developmental trajectories of infants born at less than 30 weeks' gestation on the Bayley-III Scales

Durrant, C; Wong, HS; Cole, TJ; Hutchon, B; Collier, L; Wright, A; George, C; ... Huertas Ceballos, A; + view all (2020) Developmental trajectories of infants born at less than 30 weeks' gestation on the Bayley-III Scales. Archives of Disease in Childhood - Fetal and Neonatal Edition 10.1136/archdischild-2019-317810. (In press). Green open access

[thumbnail of Durrant fig3-1.jpg]
Preview
Image
Durrant fig3-1.jpg - Accepted Version

Download (360kB) | Preview
[thumbnail of Cole_Developmental trajectories of infants born at less than 30 weeks' gestation on the Bayley-III Scales_AAM.pdf]
Preview
Text
Cole_Developmental trajectories of infants born at less than 30 weeks' gestation on the Bayley-III Scales_AAM.pdf - Accepted Version

Download (201kB) | Preview

Abstract

OBJECTIVE: To describe the cognitive, language and motor developmental trajectories of children born very preterm and to identify perinatal factors that predict the trajectories. DESIGN: Data from a cohort of 1142 infants born at <30 weeks' gestation who were prospectively assessed on the Bayley Scales of Infant and Toddler Development, third edition (Bayley-III) at 3, 6, 12 and 24 months corrected age, were analysed using the Super Imposition by Translation and Rotation (SITAR) growth curve analysis model. MAIN OUTCOME MEASURES: Developmental trajectory SITAR models for Bayley-III cognitive, language (receptive and expressive communication subscales) and motor (fine and gross motor subscales) scores. RESULTS: The successfully fitted SITAR models explained 62% of variance in cognitive development, 68% in receptive communication, 53% in fine motor and 68% in the gross motor development. There was too much variation in the expressive communication subscale to fit a SITAR model. The rate of development (gradient of the curve) best explains the variation in trajectories of development in all domains. Lower gestational age, lower birth weight and male sex significantly predicted a slower rate of development. CONCLUSION: The rate of development, rather than single time point developmental assessment, best predicts the very preterm infant's developmental trajectory and should be the focus for monitoring and early intervention.

Type: Article
Title: Developmental trajectories of infants born at less than 30 weeks' gestation on the Bayley-III Scales
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1136/archdischild-2019-317810
Publisher version: http://dx.doi.org/10.1136/archdischild-2019-317810
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions.
Keywords: bayley-III, infancy, neurodevelopment, preterm, trajectories
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Neurosciences Dept
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Population, Policy and Practice Dept
URI: https://discovery.ucl.ac.uk/id/eprint/10101239
Downloads since deposit
6,011Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item