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Sleep circuits and physiology in non-mammalian systems

Lyons, DG; Rihel, J; (2020) Sleep circuits and physiology in non-mammalian systems. Current Opinion in Physiology , 15 pp. 245-255. 10.1016/j.cophys.2020.03.006. Green open access

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Abstract

Research over the last 20 years has firmly established the existence of sleep states across the animal kingdom. Work in non-mammalian animal models such as nematodes, fruit flies, and zebrafish has now uncovered many evolutionarily conserved aspects of sleep physiology and regulation, including shared circuit architecture, homeostatic and circadian control elements, and principles linking sleep physiology to function. Non-mammalian sleep research is now shedding light on fundamental aspects of the genetic and neuronal circuit regulation of sleep, with direct implications for the understanding of how sleep is regulated in mammals.

Type: Article
Title: Sleep circuits and physiology in non-mammalian systems
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.cophys.2020.03.006
Publisher version: http://dx.doi.org/10.1016/j.cophys.2020.03.006
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Cell and Developmental Biology
URI: https://discovery.ucl.ac.uk/id/eprint/10100191
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