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The absorbing life of bile acids

Marks, J; (2020) The absorbing life of bile acids. Kidney International , 97 (6) pp. 1099-1102. 10.1016/j.kint.2020.03.020. Green open access

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Abstract

Hyperphosphatemia increases cardiovascular complications and all-cause mortality rate in patients with chronic kidney disease. Targeting the processes involved in dietary phosphate absorption is an attractive means for reducing this phosphate burden. We do not, however, fully understand this process and how it is regulated. This commentary describes recent findings regarding the novel role of bile acids in regulating paracellular phosphate (and calcium) absorption by the small intestine and the potential cellular mechanisms involved.

Type: Article
Title: The absorbing life of bile acids
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.kint.2020.03.020
Publisher version: http://dx.doi.org/10.1016/j.kint.2020.03.020
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Neuro, Physiology and Pharmacology
URI: https://discovery.ucl.ac.uk/id/eprint/10099605
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