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Psychiatric Morbidity and Its Prognosis in Posterior Reversible Encephalopathy Syndrome

Keynejad, RC; David, AS; (2020) Psychiatric Morbidity and Its Prognosis in Posterior Reversible Encephalopathy Syndrome. Journal of Neuropsychiatry and Clinical Neurosciences , 32 (4) pp. 385-388. 10.1176/appi.neuropsych.19080184. Green open access

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Abstract

Posterior reversible encephalopathy syndrome (PRES) is a clinically and radiologically diagnosed disorder distinguished by subcortical vasogenic cerebral edema. To date, its presentation has been described through summarized neurological categories, such as seizures, headaches, "confusion," and "altered mental function." This retrospective case series identified all cases of clinically confirmed, radiologically diagnosed PRES resulting in treatment in a large teaching hospital from 2010 to 2019. The authors conducted a search for the term "reversible encephalopathy" in the hospital clinical radiology information system, followed by an audit of scan reports and clinical records. The most common reasons for psychiatric referral were addictions, acute psychosis, depression, suicidality, and treatment refusal. Multidisciplinary staff should consider PRES as a rare, organic differential diagnosis for acute mental state changes. Physicians should be aware of elevated rates of post-PRES psychiatric symptoms and consider whether psychiatric consultation may enhance recovery.

Type: Article
Title: Psychiatric Morbidity and Its Prognosis in Posterior Reversible Encephalopathy Syndrome
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1176/appi.neuropsych.19080184
Publisher version: http://dx.doi.org/10.1176/appi.neuropsych.19080184
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Cerebral Disorders, Consultation-Liaison Neuropsychiatry, Hypertensive Encephalopathy, Liaison Psychiatry, Posterior Reversible Encephalopathy Syndrome (PRES)
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry
URI: https://discovery.ucl.ac.uk/id/eprint/10099324
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