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Comparative Study of the Antimicrobial Effects of Tungsten Nanoparticles and Tungsten Nanocomposite Fibres on Hospital Acquired Bacterial and Viral Pathogens

Matharu, RK; Ciric, L; Ren, G; Edirisinghe, M; (2020) Comparative Study of the Antimicrobial Effects of Tungsten Nanoparticles and Tungsten Nanocomposite Fibres on Hospital Acquired Bacterial and Viral Pathogens. Nanomaterials , 10 (6) , Article 1017. 10.3390/nano10061017. Green open access

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Abstract

A significant proportion of patients acquire hospital associated infections as a result of care within the NHS each year. Numerous antimicrobial strategies, such as antibiotics and surface modifications to medical facilities and instruments, have been devised in an attempt to reduce the incidence of nosocomial infections, but most have been proven unsuccessful and unsustainable due to antibiotic resistance. Therefore, the need to discover novel materials that can combat pathogenic microorganisms is ongoing. Novel technologies, such as the potential use of nanomaterials and nanocomposites, hold promise for reducing these infections in the fight against antimicrobial resistance. In this study, the antimicrobial activity of tungsten, tungsten carbide and tungsten oxide nanoparticles were tested against Escherichia coli, Staphylococcus aureus and bacteriophage T4 (DNA virus). The most potent nanoparticles, tungsten oxide, were incorporated into polymeric fibres using pressurised gyration and characterised using scanning electron microscopy and energy dispersive X-ray spectroscopy. The antimicrobial activity of tungsten oxide/polymer nanocomposite fibres was also studied. The results suggest the materials in this study promote mediation of the inhibition of microbial growth in suspension.

Type: Article
Title: Comparative Study of the Antimicrobial Effects of Tungsten Nanoparticles and Tungsten Nanocomposite Fibres on Hospital Acquired Bacterial and Viral Pathogens
Location: Switzerland
Open access status: An open access version is available from UCL Discovery
DOI: 10.3390/nano10061017
Publisher version: https://doi.org/10.3390/nano10061017
Language: English
Additional information: © 2020 by the Authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Keywords: antimicrobial, bacteria, nanoparticles, nosocomial infection, tungsten, tungsten oxide, virus
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Civil, Environ and Geomatic Eng
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Mechanical Engineering
URI: https://discovery.ucl.ac.uk/id/eprint/10099165
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