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Molecularly Imprinted Polymers and Electrospinning: Manufacturing Convergence for Next‐Level Applications

Patel, KD; Kim, H; Knowles, JC; Poma, A; (2020) Molecularly Imprinted Polymers and Electrospinning: Manufacturing Convergence for Next‐Level Applications. Advanced Functional Materials , Article 2001955. 10.1002/adfm.202001955. (In press). Green open access

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Abstract

Micro‐ and especially nanofiber‐type of materials are extremely attractive for a number of applications, ranging from separation and analysis to drug delivery and tissue engineering, and the majority of them are currently produced worldwide via the extremely popular and effective electrospinning technique. The addition of specific tailored molecular recognition capability to these electrospun materials via the established molecular imprinting technology can be extremely beneficial for a number of applications, as indicated by the number of examples in the literature over the past 15 years. However, the integration of these two technologies has proven to be quite challenging, mainly due to the different processing methodologies which characterize the two approaches. In this progress report, the practical difficulties related to the combination of electrospinning and molecular imprinting and to the production of molecularly imprinted electrospun fibers are addressed, discussing the main aspects to take into consideration when designing and optimizing the experimental protocols, as well as highlighting the most prolific research applications that have been explored thus far, to conclude with a commercial/industrial and economic perspective on the envisaged market for these hybrid products.

Type: Article
Title: Molecularly Imprinted Polymers and Electrospinning: Manufacturing Convergence for Next‐Level Applications
Open access status: An open access version is available from UCL Discovery
DOI: 10.1002/adfm.202001955
Publisher version: https://doi.org/10.1002/adfm.202001955
Language: English
Additional information: Copyright © 2020 The Authors. Published by WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim. This is an open access article under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Keywords: electrospinning, electrospray, molecular imprinting, molecularly imprinted polymers, nanotechnology
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Eastman Dental Institute
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Eastman Dental Institute > Biomaterials and Tissue Eng
URI: https://discovery.ucl.ac.uk/id/eprint/10099029
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