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An observational study of the lung clearance index throughout childhood in cystic fibrosis: Early years matter

Davies, G; Stanojevic, S; Raywood, E; Duncan, JA; Stocks, J; Lum, S; Bush, A; ... London Cystic Fibrosis Collaboration, .; + view all (2020) An observational study of the lung clearance index throughout childhood in cystic fibrosis: Early years matter. European Respiratory Journal , 56 (4) , Article 2000006. 10.1183/13993003.00006-2020. Green open access

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Abstract

The London Cystic Fibrosis Collaboration (LCFC) has prospectively followed a clinically diagnosed cohort of infants with cystic fibrosis (CF) born in South East England since 1999 [1–4]. Over the past twenty years, the LCFC has obtained comprehensive measures of lung function and structure, including measures of ventilation inhomogeneity (lung clearance index, LCI) and high-resolution computed tomography (HRCT) scans.

Type: Article
Title: An observational study of the lung clearance index throughout childhood in cystic fibrosis: Early years matter
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1183/13993003.00006-2020
Publisher version: https://doi.org/10.1183/13993003.00006-2020
Language: English
Additional information: http://creativecommons.org/licenses/by/4.0/ This version is distributed under the terms of the Creative Commons Attribution Licence 4.0.
Keywords: Cystic fibrosis, multiple breath washout, lung clearance index, spirometry, computed tomography, children, adolescence
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Infection, Immunity and Inflammation Dept
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Population, Policy and Practice Dept
URI: https://discovery.ucl.ac.uk/id/eprint/10098570
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