Lumby, CK;
Zhao, L;
Oporto, M;
Best, T;
Tutill, H;
Shah, D;
Veys, P;
... Breuer, J; + view all
(2020)
Favipiravir and Zanamivir Cleared Infection with Influenza B in a Severely Immunocompromised Child.
Clinical Infectious Diseases
10.1093/cid/ciaa023.
(In press).
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Abstract
A combination of favipiravir and zanamivir successfully cleared influenza B infection in a child who had undergone bone marrow transplant for X-linked severe combined immunodeficiency, with no recovery of T lymphocytes. Deep sequencing of viral samples illuminated the within-host dynamics of infection, demonstrating the effectiveness of favipiravir in this case.
| Type: | Article |
|---|---|
| Title: | Favipiravir and Zanamivir Cleared Infection with Influenza B in a Severely Immunocompromised Child |
| Location: | United States |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1093/cid/ciaa023 |
| Publisher version: | https://doi.org/10.1093/cid/ciaa023 |
| Language: | English |
| Additional information: | This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
| Keywords: | favipiravir, genome sequencing, influenza, zanamivir |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Genetics and Genomic Medicine Dept UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Infection, Immunity and Inflammation Dept |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10098331 |
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