UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

The investigation of acute optic neuritis: a review and proposed protocol

Petzold, A; Wattjes, MP; Costello, F; Flores-Rivera, J; Fraser, CL; Fujihara, K; Leavitt, J; ... Plant, GT; + view all (2014) The investigation of acute optic neuritis: a review and proposed protocol. Nature Reviews Neurology , 10 pp. 447-458. 10.1038/nrneurol.2014.108. Green open access

[thumbnail of on-invest-protocol-R1-140314.pdf]
Preview
Text
on-invest-protocol-R1-140314.pdf - Accepted Version

Download (13MB) | Preview

Abstract

Optic neuritis is an inflammatory optic neuropathy that affects many patients with multiple sclerosis (MS) at some point during their disease course. Differentiation of acute episodes of MS-associated optic neuritis from other autoimmune and inflammatory optic neuropathies is vital for treatment choice and further patient management, but is not always straightforward. Over the past decade, a number of new imaging, laboratory and electrophysiological techniques have entered the clinical arena. To date, however, no consensus guidelines have been devised to specify how and when these techniques can be most rationally applied for the diagnostic work-up of patients with acute optic neuritis. In this article, we review the literature and attempt to formulate a consensus for the investigation of patients with acute optic neuritis, both in standard care and in research with relevance to clinical treatment trials.

Type: Article
Title: The investigation of acute optic neuritis: a review and proposed protocol
Open access status: An open access version is available from UCL Discovery
DOI: 10.1038/nrneurol.2014.108
Publisher version: https://doi.org/10.1038/nrneurol.2014.108
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Diagnostic markers, Eye manifestations, Multiple sclerosis, Prognostic markers
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
URI: https://discovery.ucl.ac.uk/id/eprint/10098004
Downloads since deposit
143Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item