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Modeling of Errors due to Uncertainties in Ultrasound Sensor Locations in Photoacoustic Tomography

Sahlstrom, T; Pulkkinen, A; Tick, J; Leskinen, J; Tarvainen, T; (2020) Modeling of Errors due to Uncertainties in Ultrasound Sensor Locations in Photoacoustic Tomography. IEEE Transactions on Medical Imaging 10.1109/tmi.2020.2966297. (In press). Green open access

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Abstract

Photoacoustic tomography is an imaging modality based on the photoacoustic effect caused by the absorption of an externally introduced light pulse. In the inverse problem of photoacoustic tomography, the initial pressure generated through the photoacoustic effect is estimated from a measured photoacoustic time-series utilizing a forward model for ultrasound propagation. Due to the ill-posedness of the inverse problem, errors in the forward model or measurements can result in significant errors in the solution of the inverse problem. In this work, we study modeling of errors caused by uncertainties in ultrasound sensor locations in photoacoustic tomography using a Bayesian framework. The approach is evaluated with simulated and experimental data. The results indicate that the inverse problem of photoacoustic tomography is sensitive even to small uncertainties in sensor locations. Furthermore, these uncertainties can lead to significant errors in the estimates and reduction of the quality of the photoacoustic images. In this work, we show that the errors due to uncertainties in ultrasound sensor locations can be modeled and compensated using Bayesian approximation error modeling.

Type: Article
Title: Modeling of Errors due to Uncertainties in Ultrasound Sensor Locations in Photoacoustic Tomography
Open access status: An open access version is available from UCL Discovery
DOI: 10.1109/tmi.2020.2966297
Publisher version: https://doi.org/10.1109/tmi.2020.2966297
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Photoacoustic tomography (PAT) , inverse problems , Bayesian methods , error modeling
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Computer Science
URI: https://discovery.ucl.ac.uk/id/eprint/10097971
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