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Blood sampled from existing peripheral IV cannulae yields results equivalent to venepuncture: a systematic review

Lesser, FD; Lanham, DA; Davis, D; (2020) Blood sampled from existing peripheral IV cannulae yields results equivalent to venepuncture: a systematic review. JRSM Open , 11 (5) pp. 1-7. 10.1177/2054270419894817. Green open access

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Abstract

Objectives: To establish whether blood samples taken from used peripheral intravenous cannulae are clinically interchangeable with venepuncture. Design: Systematic review. PubMed, Web of Science and Embase were searched for relevant trials. Setting: Trials which compared blood samples from used peripheral intravenous cannulae to venepuncture and provided limits of agreement or data which allowed calculation of limits of agreement. Participants: Seven trials with 746 participants. Blood tests included 13 commonly ordered biochemistry, haematology and blood gas measurements. Main outcome measures: 95% limits of agreement. Data were pooled using inverse variance weighting and compared to a clinically acceptable range estimated by expert opinion from previous trials. Results: Limits of agreement for blood samples from used peripheral intravenous cannulae were within the clinically acceptable range for sodium, chloride, urea, creatinine and haematology samples. Limits of agreement for potassium were 0.47 mmol/L which exceeded the clinically acceptable range. Peripheral intravenous cannula samples for blood gas analysis gave limits of agreement which far exceeded the clinically acceptable range. Conclusions: Blood sampling from used peripheral intravenous cannulae is a reasonable clinical practice for haematology and biochemistry samples. Potassium samples from used peripheral intravenous cannulae can be used in situations where error up to 0.47 mmol/L is acceptable. Peripheral intravenous cannula samples should not be used for blood gas analysis.

Type: Article
Title: Blood sampled from existing peripheral IV cannulae yields results equivalent to venepuncture: a systematic review
Open access status: An open access version is available from UCL Discovery
DOI: 10.1177/2054270419894817
Publisher version: https://doi.org/10.1177/2054270419894817
Language: English
Additional information: This article is distributed under the terms of the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed
Keywords: Venepuncture, blood sampling, peripheral venous cannula, phlebotomy
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Population Science and Experimental Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Population Science and Experimental Medicine > MRC Unit for Lifelong Hlth and Ageing
URI: https://discovery.ucl.ac.uk/id/eprint/10097706
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