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The modified arterial reservoir: An update with consideration of asymptotic pressure (P∞) and zero-flow pressure (Pzf)

Hughes, AD; Parker, KH; (2020) The modified arterial reservoir: An update with consideration of asymptotic pressure (P∞) and zero-flow pressure (Pzf). Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine , 234 (11) pp. 1288-1299. 10.1177/0954411920917557. Green open access

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Abstract

This article describes the modified arterial reservoir in detail. The modified arterial reservoir makes explicit the wave nature of both reservoir (Pres) and excess pressure (Pxs). The mathematical derivation and methods for estimating Pres in the absence of flow velocity data are described. There is also discussion of zero-flow pressure (Pzf), the pressure at which flow through the circulation ceases; its relationship to asymptotic pressure (P∞) estimated by the reservoir model; and the physiological interpretation of Pzf . A systematic review and meta-analysis provides evidence that Pzf differs from mean circulatory filling pressure.

Type: Article
Title: The modified arterial reservoir: An update with consideration of asymptotic pressure (P∞) and zero-flow pressure (Pzf)
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1177/0954411920917557
Publisher version: https://doi.org/10.1177/0954411920917557
Language: English
Additional information: This article is distributed under the terms of the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
Keywords: Geometrical imperfection, Hemodynamics, blood pressure, circulation
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Population Science and Experimental Medicine
URI: https://discovery.ucl.ac.uk/id/eprint/10097066
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