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Nutcracker syndrome mimicking new daily persistent headache: A case report

Stubberud, A; Cheema, S; Tronvik, E; Matharu, M; (2020) Nutcracker syndrome mimicking new daily persistent headache: A case report. Cephalalgia , 40 (9) pp. 1008-1011. 10.1177/0333102420918554. Green open access

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Abstract

INTRODUCTION: Compression of the duodenum and left renal vein between the aorta and superior mesenteric artery usually leads to symptoms of proximal bowel obstruction or hematuria and, more rarely, nonspecific mild headaches. CASE: A young woman presented with new daily persistent headache refractory to numerous pharmacological treatments, onabotulinumtoxinA, nerve blocks, and occipital nerve stimulation. Following several years of daily severe headache, worsening abdominal pain and intolerance for food intake led to the discovery of aortomesenteric compression. Surgical treatment gave prompt improvement in gastric symptoms but also essentially resolved the headache. CONCLUSION: This is the first description of new daily persistent headache in association with aortomesenteric compression as well as marked improvement of headache following aortomesenteric decompression. In patients with new daily persistent headache and orthostatic symptoms one may consider a differential diagnosis of Nutcracker syndrome, especially in patients with comorbid hypermobility syndromes, hematuria or gastric symptoms.

Type: Article
Title: Nutcracker syndrome mimicking new daily persistent headache: A case report
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1177/0333102420918554
Publisher version: https://doi.org/10.1177/0333102420918554
Language: English
Additional information: © 2021 by International Headache Society. This article is distributed under the terms of the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/).
Keywords: CSF pressure, Nutcracker syndrome, Superior mesenteric artery syndrome, surgery
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Brain Repair and Rehabilitation
URI: https://discovery.ucl.ac.uk/id/eprint/10096286
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