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Type I collagen structure, synthesis, and regulation

Bou-Gharios, G; Abraham, D; de Crombrugghe, B; (2020) Type I collagen structure, synthesis, and regulation. In: Bilezikian, J and Martin, TJ and Rosen, C, (eds.) Principles of Bone Biology. (pp. 295-337). Elsevier: Leiden, The Netherlands.

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Abstract

It has been over 150 years since the term “collagen” was first adopted in the English language. This ropelike structure that yields gelatin upon boiling made its early appearance in evolution in primitive animals such as jellyfish, coral, and sea anemones. Today, the collagen family of proteins has grown to 28 different types and is used as a versatile biomaterial for delivery of drugs as well as for cosmetic purposes.

Type: Book chapter
Title: Type I collagen structure, synthesis, and regulation
ISBN-13: 9780128148419
DOI: 10.1016/B978-0-12-814841-9.00013-0
Publisher version: https://doi.org/10.1016/B978-0-12-814841-9.00013-0
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Bone pathology, Collagen assembly, Fibrillar collagen, Fibrillogenesis, Transcription regulation, Type I collagen
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Inflammation
URI: https://discovery.ucl.ac.uk/id/eprint/10096256
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