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Thermoplasmonic ssDNA Dynamic Release from Gold Nanoparticles Examined with Advanced Fluorescence Microscopy

Simonceli, S; Weerasekera, HDA; Fasciani, C; Boddy, CN; Aramendia, PF; Alarcon, EI; Scaiano, JC; (2015) Thermoplasmonic ssDNA Dynamic Release from Gold Nanoparticles Examined with Advanced Fluorescence Microscopy. Journal of Physical Chemistry Letters , 6 (8) pp. 1499-1503. 10.1021/acs.jpclett.5b00272. Green open access

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Abstract

Plasmon excitation of spherical gold nanoparticles carrying a fluorescent labeled 30 bp dsDNA cargo, with one chain covalently attached through two S–Au bonds to the surface, results in release of the complementary strand as ssDNA that can be examined in situ using high-resolution fluorescence microscopy. The release is dependent on the total energy delivered, but not the rate of delivery, an important property for plasmonic applications in medicine, sensors, and plasmon-induced PCR.

Type: Article
Title: Thermoplasmonic ssDNA Dynamic Release from Gold Nanoparticles Examined with Advanced Fluorescence Microscopy
Open access status: An open access version is available from UCL Discovery
DOI: 10.1021/acs.jpclett.5b00272
Publisher version: https://doi.org/10.1021/acs.jpclett.5b00272
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Plasmonics, DNA, nanotechnology, gold nanoparticles
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > London Centre for Nanotechnology
URI: https://discovery.ucl.ac.uk/id/eprint/10096099
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