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Functional imaging of the piriform cortex in focal epilepsy

Koepp, M; Galovic, M; (2020) Functional imaging of the piriform cortex in focal epilepsy. Experimental Neurology , 330 , Article 113305. 10.1016/j.expneurol.2020.113305. Green open access

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Abstract

Experiments in animal models have identified specific brain regions such as the deep anterior piriform cortex as important for controlling the initiation or propagation of both generalized and focal seizure activity. However, there is little experimental evidence to translate these observations to the control of focal seizures in humans. Here, we summarize findings from different hemodynamic and neurotransmitter functional imaging studies in groups of patients with focal epilepsies arising from different cortical locations in support of a common area of brain dysfunction in focal epilepsies.

Type: Article
Title: Functional imaging of the piriform cortex in focal epilepsy
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.expneurol.2020.113305
Publisher version: https://doi.org/10.1016/j.expneurol.2020.113305
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: BOLD, EEG/fMRI, Flumazenil-PET, Focal epilepsy, Subcortical
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Clinical and Experimental Epilepsy
URI: https://discovery.ucl.ac.uk/id/eprint/10095696
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