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Objective method for measuring the macular pigment optical density in the eye

Christaras, D; Ginis, H; Pennos, A; Mompean, J; Artal, P; (2019) Objective method for measuring the macular pigment optical density in the eye. Biomedical Optics Express , 10 (7) pp. 3572-3583. 10.1364/BOE.10.003572. Green open access

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Abstract

Macular pigment is a yellowish pigment of purely dietary origin, which is thought to have a protective role in the retina. Recently, it was linked to age-related macular degeneration and improved visual function. In this work, we present a method and a corresponding optical instrument for the rapid measurement of its optical density. The method is based on fundus reflectometry and features a photodetector for the measurement of reflectance at different wavelengths and retinal locations. The method has been tested against a commercially available instrument on a group of healthy volunteers and has shown good correlation. The proposed instrument can serve as a rapid, non-midriatic, low-cost tool for the measurement of macular pigment optical density.

Type: Article
Title: Objective method for measuring the macular pigment optical density in the eye
Open access status: An open access version is available from UCL Discovery
DOI: 10.1364/BOE.10.003572
Publisher version: https://doi.org/10.1364/BOE.10.003572
Language: English
Additional information: © 2019 Optical Society of America under the terms of the OSA Open Access Publishing Agreement https://www.osapublishing.org/library/license_v1.cfm#VOR-OA
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Ophthalmology
URI: https://discovery.ucl.ac.uk/id/eprint/10094833
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