UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Factors associated with hospitalisation among people with Parkinson's disease – A systematic review and meta-analysis

Okunoye, O; Kojima, G; Marston, L; Walters, K; Schrag, A; (2020) Factors associated with hospitalisation among people with Parkinson's disease – A systematic review and meta-analysis. Parkinsonism & Related Disorders , 71 pp. 66-72. 10.1016/j.parkreldis.2020.02.018. Green open access

[img]
Preview
Text
Marston_Clean manuscript - all revisions incorporated within text.pdf - Accepted version

Download (405kB) | Preview

Abstract

INTRODUCTION: Parkinson's disease (PD) is associated with an increased risk of admission to hospital, however data on the main reasons for admission is lacking. Our objective was to determine the pooled prevalence of the most common factors leading to admissions among people with Parkinson's disease. METHODOLOGY: MA systematic literature search was conducted in 11 electronic databases. We included all studies providing reasons for admissions among PD patients without restrictions to diagnostic criteria of PD, language or year of study. In the included studies, methodological quality, publication bias and heterogeneity were assessed. Meta-analysis was performed using random-effects models to calculate the pooled estimates of the identified top factors that lead to admission among people with PD. RESULTS: A total of 7283 studies were identified of which nine studies including 7162 people with PD were included in this review. There was a high degree of heterogeneity between studies regarding reasons for hospitalisation. The pooled prevalence of the topmost reasons for hospitalisation among people with PD was 22%(95%CI 16.0%-30.0%) for infections (mainly urinary tract infections and pneumonia); 19%(95%CI 13.0%-27.0%) for worsening motor manifestations of PD; 18%(95%CI 14.0%-21.0%) for falls/fractures; 13%(95%CI 9.0%-18%) for cardiovascular co-morbidities; 8%(95%CI 4.0%-13.0%) for neuropsychiatric and 7%(95%CI 4.0%-11.0%) gastrointestinal complications. CONCLUSION: The main reasons for hospitalisation among people with PD are infections, worsening motor features, falls/fractures, cardiovascular co-morbidities, neuropsychiatric and gastrointestinal complications. Further research is needed in targeting and implementing preventative strategies.

Type: Article
Title: Factors associated with hospitalisation among people with Parkinson's disease – A systematic review and meta-analysis
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.parkreldis.2020.02.018
Publisher version: http://dx.doi.org/10.1016/j.parkreldis.2020.02.018
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Admissions, Factors, Hospitalisation, Parkinson's disease, Prevalence
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Clinical and Movement Neurosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Primary Care and Population Health
URI: https://discovery.ucl.ac.uk/id/eprint/10093396
Downloads since deposit
14Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item