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Simplified retrieval method for Edge illumination X-ray phase contrast imaging allowing multi-modal imaging with fewer input frames

Buchanan, I; Mittone, A; Bravin, A; Diemoz, P; Endrizzi, M; Olivo, A; (2020) Simplified retrieval method for Edge illumination X-ray phase contrast imaging allowing multi-modal imaging with fewer input frames. Optics Express , 28 (8) pp. 11597-11608. 10.1364/OE.372312. Green open access

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Abstract

We present data from an implementation of Edge Illumination (EI) that uses a detector aperture designed for increasing dynamic range, suitable for clinically relevant X-ray energies and demonstrated here using synchrotron radiation. By utilising a sufficiently large crosstalk between pixels, this implementation enables single-scan imaging for phase and absorption, and double-scan for phase, absorption and dark field imaging. The presence of the detector mask enables a direct comparison between conventional EI and beam tracking (BT), which we conduct through Monte Carlo and analytical modelling in the case of a single-scan being used for the retrieval of all three contrasts. In the present case, where the X-ray beam width is comparable to the pixel size, we provide an analysis on best-positioning of the beam on the detector for accurate signal retrieval. Further, we demonstrate an application of this method by distinguishing different concentrations of microbubbles via their dark field signals at high energy using an EI system.

Type: Article
Title: Simplified retrieval method for Edge illumination X-ray phase contrast imaging allowing multi-modal imaging with fewer input frames
Open access status: An open access version is available from UCL Discovery
DOI: 10.1364/OE.372312
Publisher version: https://doi.org/10.1364/OE.372312
Language: English
Additional information: Published by The Optical Society under the terms of the Creative Commons Attribution 4.0 License. Further distribution of this work must maintain attribution to the author(s) and the published article's title, journal citation, and DOI.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/10092951
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