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The Impact of Metabolic Syndrome and Lifestyle Habits on the Risk of the First Event of Cardiovascular Disease: Results from a Cohort Study in Lithuanian Urban Population

Jasiukaitiene, V; Luksiene, D; Tamosiunas, A; Radisauskas, R; Bobak, M; (2020) The Impact of Metabolic Syndrome and Lifestyle Habits on the Risk of the First Event of Cardiovascular Disease: Results from a Cohort Study in Lithuanian Urban Population. Medicina , 56 (1) , Article 18. 10.3390/medicina56010018. Green open access

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Abstract

BACKGROUND AND OBJECTIVES: In recent years, the impact of individual risk factors on mortality from cardiovascular diseases (CVD) has been often investigated. However, there is a lack of studies that have evaluated the relationship between lifestyle habits, metabolic syndrome, and their combined influence on the first event of CVD. The aim of this study was to investigate the impact of metabolic syndrome and lifestyle habits on the risk of the first event of CVD in a Lithuanian urban population. MATERIALS AND METHODS: The presented data were collected from a survey that was carried out within the framework of the international project Health, Alcohol and Psychosocial Factors in Eastern Europe (HAPIEE). For statistical analysis, 4257 participants aged 45–72 years were selected (with a follow-up of 11 years). RESULTS: The findings from the Cox proportional hazards regression multivariable analysis showed that metabolic syndrome, current smoking status, and former smoking status increased the risk of the first event of CVD among men (with respective hazard ratios (HR) of 1.53, 1.94, and 1.43; p < 0.01). In women, metabolic syndrome increased the risk of the first event of CVD (HR = 1.56; p = 0.001), while the increased consumption of fresh vegetables and fruits decreased the risk of the first event of CVD (HR = 0.80; p = 0.003). Multivariable logistic regression analysis results show that a level of increased physical activity by one hour can be linked to a lower risk of metabolic syndrome by 2% among men (odds ratio (OR) = 0.98; p = 0.001). CONCLUSIONS: Metabolic syndrome and lifestyle habits including cigarette smoking in men and low consumption of fresh vegetables and fruits in women are strong predictors of the first event of CVD.

Type: Article
Title: The Impact of Metabolic Syndrome and Lifestyle Habits on the Risk of the First Event of Cardiovascular Disease: Results from a Cohort Study in Lithuanian Urban Population
Open access status: An open access version is available from UCL Discovery
DOI: 10.3390/medicina56010018
Publisher version: https://doi.org/10.3390/medicina56010018
Language: English
Additional information: © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Keywords: metabolic syndrome, nutrition habits, smoking, physical activity, cardiovascular diseases
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Epidemiology and Public Health
URI: https://discovery.ucl.ac.uk/id/eprint/10092779
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