Breyer, RM;
Clapp, L;
Coleman, RA;
Giembycz, M;
Heinemann, A;
Hills, R;
Jones, RL;
... Yao, C; + view all
(2019)
Prostanoid receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database.
IUPHAR/BPS Guide to Pharmacology CITE
, 2019
(4)
10.2218/gtopdb/f58/2019.4.
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Abstract
Prostanoid receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Prostanoid Receptors [644]) are activated by the endogenous ligands prostaglandins PGD2, PGE1, PGE2 , PGF2α, PGH2, prostacyclin [PGI2] and thromboxane A2. Measurement of the potency of PGI2 and thromboxane A2 is hampered by their instability in physiological salt solution; they are often replaced by cicaprost and U46619, respectively, in receptor characterization studies.
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