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Substituted hydroxyapatite: a recent development

Jiang, Y; Yuan, Z; Huang, J; (2020) Substituted hydroxyapatite: a recent development. Materials Technology , 35 (11-12) pp. 785-796. 10.1080/10667857.2019.1664096. Green open access

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Abstract

Hydroxyapatite (HA, Ca10(PO4)6(OH)2) constitutes the major inorganic hard tissues, such as bone and teeth. Various substitutions in the apatite structure have been developed for a wide range of biomedical applications, such as the bone repair and tissue regenerations; bioactive and/or antibacterial coating for medical devices, biomarkers or carriers in drug/gene delivery systems, and the biomagnetic agents for cancer treatment. In this review, the recent development on substituted HA was overviewed from the aspects of enhanced osteoconductivity and multifunctionality of mono- and multi-cationic and anionic substitutions.

Type: Article
Title: Substituted hydroxyapatite: a recent development
Open access status: An open access version is available from UCL Discovery
DOI: 10.1080/10667857.2019.1664096
Publisher version: https://doi.org/10.1080/10667857.2019.1664096
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Hydroxyapatites, co-substitution, osteoconductivity, antibacterial, multifunctionality, drug delivery
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Mechanical Engineering
URI: https://discovery.ucl.ac.uk/id/eprint/10092303
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