Gouge, J;
Vannini, A;
(2018)
New tricks for an old dog: Brf2-dependent RNA Polymerase III transcription in oxidative stress and cancer.
Transcription
, 9
(1)
pp. 61-66.
10.1080/21541264.2017.1335269.
Preview |
Text
New tricks for an old dog Brf2-dependent RNA Polymerase III transcription in oxidative stress and cancer.pdf - Published Version Download (538kB) | Preview |
Abstract
Here, we discuss the role of Brf2, an RNA Polymerase III core transcription factor, as a master switch of the oxidative stress response. We highlight the interplay of Brf2 with the Nrf2/Keap1 pathway, as well as the role of Brf2 in cancer and other possible regulations.
| Type: | Article |
|---|---|
| Title: | New tricks for an old dog: Brf2-dependent RNA Polymerase III transcription in oxidative stress and cancer |
| Location: | United States |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1080/21541264.2017.1335269 |
| Publisher version: | https://doi.org/10.1080/21541264.2017.1335269 |
| Language: | English |
| Additional information: | This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/ 4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way. |
| Keywords: | Brf2, Nrf2, RNA polymerase III, redox stress, transcription, Humans, Neoplasms, Oxidative Stress, RNA Polymerase III, Transcription Factor TFIIIB, Transcription, Genetic |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Structural and Molecular Biology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10091774 |
Downloads since deposit
93Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months
Archive Staff Only
 |
View Item |
