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Prostanoid receptors (version 2019.5) in the IUPHAR/BPS Guide to Pharmacology Database

Breyer, RM; Clapp, L; Coleman, RA; Giembycz, M; Heinemann, A; Hills, R; Jones, RL; ... Yao, C; + view all (2019) Prostanoid receptors (version 2019.5) in the IUPHAR/BPS Guide to Pharmacology Database. IUPHAR/BPS Guide to Pharmacology CITE , 2019 (5) 10.2218/gtopdb/F58/2019.5. Green open access

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Abstract

Prostanoid receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Prostanoid Receptors [659]) are activated by the endogenous ligands prostaglandins PGD2, PGE1, PGE2 , PGF2α, PGH2, prostacyclin [PGI2] and thromboxane A2. Measurement of the potency of PGI2 and thromboxane A2 is hampered by their instability in physiological salt solution; they are often replaced by cicaprost and U46619, respectively, in receptor characterization studies.

Type: Article
Title: Prostanoid receptors (version 2019.5) in the IUPHAR/BPS Guide to Pharmacology Database
Open access status: An open access version is available from UCL Discovery
DOI: 10.2218/gtopdb/F58/2019.5
Publisher version: http://journals.ed.ac.uk/gtopdb-cite/article/view/...
Language: English
Additional information: This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-sa/4.0/).
Keywords: Prostaniod receptors, Prostaglandins
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Pre-clinical and Fundamental Science
URI: https://discovery.ucl.ac.uk/id/eprint/10091570
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