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Stereoscopic Vision in Macular Telangiectasia Type 2

Mueller, S; Heeren, TFC; Nadal, J; Issa, PC; Herrmann, P; Holz, FG; Wabbels, BK; (2019) Stereoscopic Vision in Macular Telangiectasia Type 2. Ophthalmologica , 241 (3) pp. 121-129. 10.1159/000492134. Green open access

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Abstract

PURPOSE: To investigate stereoscopic vision in patients with macular telangiectasia type 2 and correlate a paracentral sensitivity loss to reduced stereoscopic function. METHODS: In a prospective single-center study, 50 patients with macular telangiectasia type 2 and 25 age-matched controls were investigated. Stereoscopic function was evaluated with Lang I, Titmus and TNO-test. Sensitivity of the central 16° was tested using fundus-controlled perimetry (microperimetry). Functional loss was quantified as depth, size and localization of scotomata. RESULTS: Both Titmus and TNO-test revealed significantly reduced stereoscopic vision in patients compared to controls (both, p<0.0001). This applied even to patients with only relative or monocular paracentral scotomata. A strong correlation was observed for reduced stereoscopic vision with horizontal scotoma size and with the distance of scotomata from the foveal center. CONCLUSIONS: The results indicate that stereoscopic vision is impaired early in patients with MacTel type 2. A paracentral sensitivity loss, even if mild and limited to one eye, may considerably interfere with stereoscopic function despite normal visual acuity. Projection of paracentral scotomata within the patient`s central visual field plays an important role in stereoscopic vision and should be considered when interpreting stereoscopic test results.

Type: Article
Title: Stereoscopic Vision in Macular Telangiectasia Type 2
Open access status: An open access version is available from UCL Discovery
DOI: 10.1159/000492134
Publisher version: https://doi.org/10.1159/000492134
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Ophthalmology
URI: https://discovery.ucl.ac.uk/id/eprint/10090983
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