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The Genomic Impact of European Colonization of the Americas

Ongaro, L; Scliar, MO; Flores, R; Raveane, A; Marnetto, D; Sarno, S; Gnecchi-Ruscone, GA; ... Montinaro, F; + view all (2019) The Genomic Impact of European Colonization of the Americas. Current Biology , 29 (23) 3974-3986.e4. 10.1016/j.cub.2019.09.076. Green open access

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Abstract

The human genetic diversity of the Americas has been affected by several events of gene flow that have continued since the colonial era and the Atlantic slave trade. Moreover, multiple waves of migration followed by local admixture occurred in the last two centuries, the impact of which has been largely unexplored. Here, we compiled a genome-wide dataset of ∼12,000 individuals from twelve American countries and ∼6,000 individuals from worldwide populations and applied haplotype-based methods to investigate how historical movements from outside the New World affected (1) the genetic structure, (2) the admixture profile, (3) the demographic history, and (4) sex-biased gene-flow dynamics of the Americas. We revealed a high degree of complexity underlying the genetic contribution of European and African populations in North and South America, from both geographic and temporal perspectives, identifying previously unreported sources related to Italy, the Middle East, and to specific regions of Africa.

Type: Article
Title: The Genomic Impact of European Colonization of the Americas
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.cub.2019.09.076
Publisher version: https://doi.org/10.1016/j.cub.2019.09.076
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Atlantic Slave Trade, European colonization, admixture history of the Americas, sex-biased admixture
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Genetics, Evolution and Environment
URI: https://discovery.ucl.ac.uk/id/eprint/10086996
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