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Molecularly Imprinted Polymers for Cell Recognition

Piletsky, S; Canfarotta, F; Poma, A; Bossi, AM; Piletsky, S; (2020) Molecularly Imprinted Polymers for Cell Recognition. Trends in Biotechnology , 38 (4) pp. 368-387. 10.1016/j.tibtech.2019.10.002. Green open access

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Abstract

Since their conception 50 years ago, molecularly imprinted polymers (MIPs) have seen extensive development both in terms of synthetic routes and applications. Cells are perhaps the most challenging target for molecular imprinting. Although early work was based almost entirely around microprinting methods, recent developments have shifted towards epitope imprinting to generate MIP nanoparticles (NPs). Simultaneously, the development of techniques such as solid phase MIP synthesis has solved many historic issues of MIP production. This review briefly describes various approaches used in cell imprinting with a focus on applications of the created materials in imaging, drug delivery, diagnostics, and tissue engineering.

Type: Article
Title: Molecularly Imprinted Polymers for Cell Recognition
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.tibtech.2019.10.002
Publisher version: https://doi.org/10.1016/j.tibtech.2019.10.002
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: molecularly imprinted polymers (MIPs), cell recognition, epitopes, targeted delivery, sensors, stem cells
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Eastman Dental Institute
URI: https://discovery.ucl.ac.uk/id/eprint/10086838
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