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Randomised controlled trial of the effect of Tai Chi on postural balance of people with dementia

Nyman, SR; Ingram, W; Sanders, J; Thomas, P; Thomas, S; Vassallo, M; Raftery, J; ... Barrado-Martín, Y; + view all (2019) Randomised controlled trial of the effect of Tai Chi on postural balance of people with dementia. Clinical Interventions in Aging , 14 pp. 2017-2029. 10.2147/CIA.S228931. Green open access

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Abstract

PURPOSE: To investigate the effect of Tai Chi exercise on postural balance among people with dementia (PWD) and the feasibility of a definitive trial on falls prevention. PATIENTS AND METHODS: Dyads, comprising community-dwelling PWD and their informal carer (N=85), were randomised to usual care (n=43) or usual care plus weekly Tai Chi classes and home practice for 20 weeks (n=42). The primary outcome was the timed up and go test. All outcomes for PWD and their carers were assessed six months post-baseline, except for falls, which were collected prospectively over the six-month follow-up period. RESULTS: For PWD, there was no significant difference at follow-up on the timed up and go test (mean difference [MD] = 0.82, 95% confidence interval [CI] = −2.17, 3.81). At follow-up, PWD in the Tai Chi group had significantly higher quality of life (MD = 0.051, 95% CI = 0.002, 0.100, standardised effect size [ES] = 0.51) and a significantly lower rate of falls (rate ratio = 0.35, 95% CI =0.15, 0.81), which was no longer significant when an outlier was removed. Carers in the Tai Chi group at follow-up were significantly worse on the timed up and go test (MD = 1.83, 95% CI = 0.12, 3.53, ES = 0.61). The remaining secondary outcomes were not significant. No serious adverse events were related to participation in Tai Chi. CONCLUSION: With refinement, this Tai Chi intervention has potential to reduce the incidence of falls and improve quality of life among community-dwelling PWD [Trial registration: NCT02864056].

Type: Article
Title: Randomised controlled trial of the effect of Tai Chi on postural balance of people with dementia
Open access status: An open access version is available from UCL Discovery
DOI: 10.2147/CIA.S228931
Publisher version: https://doi.org/10.2147/CIA.S228931
Language: English
Additional information: © 2019 Nyman et al. This work is published by Dove Medical Press Limited, and licensed under a Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/).
Keywords: accidental falls, clinical trial, cognitive impairment, exercise, intervention
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Primary Care and Population Health
URI: https://discovery.ucl.ac.uk/id/eprint/10086296
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