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A response to critiques of "The reproducibility of research and the misinterpretation of p-values"

Colquhoun, D; (2019) A response to critiques of "The reproducibility of research and the misinterpretation of p-values". Royal Society Open Science , 6 (11) , Article 190819. 10.1098/rsos.190819. Green open access

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Abstract

I proposed (8, 1, 3) that p values should be supplemented by an estimate of the false positive risk (FPR). FPR was defined as the probability that, if you claim that there is a real effect on the basis of p value from a single unbiased experiment, that you will be mistaken and the result has occurred by chance. This is a Bayesian quantity and that means that there is an infinitude of ways to calculate it. My choice of a way to estimate FPR was, therefore, arbitrary. I maintain that it is a reasonable way, and has the advantage of being mathematically simpler than other proposals and easier to understand than other methods. This might make it more easily accepted by users. As always, not every statistician agrees. This paper is a response to a critique of my 2017 paper (1) by Arandjelovic (2)

Type: Article
Title: A response to critiques of "The reproducibility of research and the misinterpretation of p-values"
Open access status: An open access version is available from UCL Discovery
DOI: 10.1098/rsos.190819
Publisher version: https://doi.org/10.1098/rsos.190819
Language: English
Additional information: Copyright © 2019 The Authors. Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
URI: https://discovery.ucl.ac.uk/id/eprint/10085940
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