Kittler, NW;
Mathes, EF;
Kinsler, V;
Frieden, IJ;
(2019)
The biker-glove pattern of congenital melanocytic nevi.
Pediatric Dermatology
, 36
(6)
pp. 918-921.
10.1111/pde.13939.
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Abstract
Congenital melanocytic nevi (CMN) are common birthmarks with 20% occurring on the limbs. We describe 4 patients with acral CMN with a “biker‐glove” distribution with sparing of the distal digits, as has previously been described in acral infantile hemangiomas (IH). The existence of the biker‐glove pattern suggests that CMN arise from early mutations in melanocyte precursors and supports the recently described Kinsler‐Larue hypothesis of mesenchymal distribution of melanocyte migration occurring in a circular field from a central point. Developmental errors in mesenchymal precursors with similar migration patterns may explain this shared pattern among CMN and IH.
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