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The Role of Epistemic Trust in the Treatment of Major Depressive Disorder

Wickham, Abbie Louise; (2019) The Role of Epistemic Trust in the Treatment of Major Depressive Disorder. Doctoral thesis (D.Clin.Psy), UCL (University College London). Green open access

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Abstract

Aims: To assess whether individuals with a mental disorder or personality disorder experience more subjective loneliness than healthy controls. Methods: PsycINFO, EMBASE, MEDLINE and Web of Science were searched using terms related to mental disorders, personality disorders and loneliness. The search yielded 452 papers, for which twenty-two met the review criteria, with nineteen being used in the meta-analysis due to missing data. As a number of these studies included more than one “patient” participant group, thirty effect sizes were included in the overall meta-analysis. Results: An overall significant large positive effect of mental disorder/personality disorder on loneliness (d=1.15) was found. Due to significant heterogeneity between the studies, post-hoc analyses were conducted to explore this. No significant effect of loneliness measurement type or study quality was found. A significant effect of disorder category (personality disorder, mood disorder, anxiety disorder, psychosis, eating disorder or mixed mental disorder) was found. A further meta-analysis excluding studies of personality disorders found a lower, but significant large positive effect of mental disorder on loneliness (d=1.03) with no heterogeneity between studies. A meta-analysis looking only at personality disorder found a higher overall significant large positive effect on loneliness (d=2.23). Conclusions: This review found evidence that individuals with mental disorders and/or personality disorders are lonelier than those without any psychopathology. The results suggest that this relationship is stronger for personality disorders. However, it is difficult to draw conclusions due to various limitations, including a lack of studies exploring certain disorders and unrepresentative samples.

Type: Thesis (Doctoral)
Qualification: D.Clin.Psy
Title: The Role of Epistemic Trust in the Treatment of Major Depressive Disorder
Event: UCL (University College London)
Open access status: An open access version is available from UCL Discovery
Language: English
Additional information: Copyright © The Author 2019. Original content in this thesis is licensed under the terms of the Creative Commons Attribution 4.0 International (CC BY 4.0) Licence (https://creativecommons.org/licenses/by/4.0/). Any third-party copyright material present remains the property of its respective owner(s) and is licensed under its existing terms. Access may initially be restricted at the author’s request.
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
URI: https://discovery.ucl.ac.uk/id/eprint/10083668
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