Davies, BM;
Smith, J;
Rikabi, S;
Wartolowska, K;
Morrey, M;
French, A;
MacLaren, R;
... Brindley, D; + view all
(2017)
A quantitative, multi-national and multi-stakeholder assessment of barriers to the adoption of cell therapies.
Journal of Tissue Engineering
, 8
pp. 1-8.
10.1177/2041731417724413.
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Abstract
Cellular therapies, such as stem cell–based treatments, have been widely researched and numerous products and treatments have been developed. Despite this, there has been relatively limited use of these technologies in the healthcare sector. This study sought to investigate the perceived barriers to this more widespread adoption. An anonymous online questionnaire was developed, based on the findings of a pilot study. This was distributed to an audience of clinicians, researchers and commercial experts in 13 countries. The results were analysed for all respondents, and also sub-grouped by geographical region, and by profession of respondents. The results of the study showed that the most significant barrier was manufacturing, with other factors such as efficacy, regulation and cost-effectiveness being identified by the different groups. This study further demonstrates the need for these important issues to be addressed during the development of cellular therapies to enable more widespread adoption of these treatments.
| Type: | Article |
|---|---|
| Title: | A quantitative, multi-national and multi-stakeholder assessment of barriers to the adoption of cell therapies |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1177/2041731417724413 |
| Publisher version: | https://doi.org/10.1177/2041731417724413 |
| Language: | English |
| Additional information: | This article is distributed under the terms of the Creative Commons Attribution 4.0 License (http://www.creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
| Keywords: | Cell- and tissue-based therapy, regenerative medicine, stem cells, translational medical research, clinical adoption |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > The Ear Institute |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10082363 |
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