UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Neuroimaging markers of motor function in children with cerebral palsy

Soskic, Sonja; (2019) Neuroimaging markers of motor function in children with cerebral palsy. Doctoral thesis (Ph.D), UCL (University College London).

Full text not available from this repository.

Abstract

Cerebral palsy (CP) is one of the most common causes of childhood physical disability. Despite extensive research, brain structure–motor function relationships are yet to be fully established. // The aim of this thesis was to use advanced diffusion MRI and an individualised approach in a small heterogeneous group of children with CP to identify and quantify changes in brain structure that are consistent and related to measures of sensorimotor function. The following analyses were employed: connectivity-based parcellation of subcortical structures, assessment of diffusion parameters of subcortical structures, and evaluation of white matter pathways involved in sensorimotor function using tractography, diffusion tensor imaging and advanced diffusion models. // Overall, the findings of this thesis indicate that properties of structures and pathways assessed at the level of the brainstem and cerebellum may be closely related to measures of motor function in children with CP. These findings could provide guidance for future larger studies aiming to establish clinically useful imaging markers of motor function in patients with CP.

Type: Thesis (Doctoral)
Qualification: Ph.D
Title: Neuroimaging markers of motor function in children with cerebral palsy
Language: English
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Neurosciences Dept
URI: https://discovery.ucl.ac.uk/id/eprint/10082294
Downloads since deposit
0Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item