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Improved iterative tomographic reconstruction for x-ray imaging with edge-illumination

Modregger, P; Meganck, J; Hagen, CK; Massimi, L; Olivo, A; Endrizzi, M; (2019) Improved iterative tomographic reconstruction for x-ray imaging with edge-illumination. Physics in Medicine and Biology 10.1088/1361-6560/ab439d. (In press). Green open access

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Endrizzi_OA_Modregger+et+al_2019_Phys._Med._Biol._10.1088_1361-6560_ab439d.pdf - Accepted Version

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Abstract

Iterative tomographic reconstruction has been established as a viable alternative for data analysis in phasesensitive x-ray imaging based on the edge-illumination principle. However, previously published approaches did not account for drifts of optical elements during a scan, which can lead to artefacts. Up to now, the strategy
 to reduce these artefacts was to acquire additional intermediate flat field images, which were used to correct the sinograms. Here, we expand the theoretical model to take these effects into account and demonstrate a significant reduction of (ring)-artefacts in the final reconstructions, while allowing for a significant reduction of scan time and dose. We further improve the model by including the capability to reconstruct combined absorption and phase contrast slices, which we experimentally demonstrate to deliver improved contrast to noise ratios compared to previously employed single shot approaches.

Type: Article
Title: Improved iterative tomographic reconstruction for x-ray imaging with edge-illumination
Open access status: An open access version is available from UCL Discovery
DOI: 10.1088/1361-6560/ab439d
Publisher version: https://doi.org/10.1088/1361-6560/ab439d
Language: English
Additional information: As the Version of Record of this article is going to be / has been published on a gold open access basis under a CC BY 3.0 licence, this Accepted Manuscript is available for reuse under a CC BY 3.0 licence immediately.
Keywords: edge illumination, iterative tomographic reconstruction, x-ray phase contrast imaging
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/10081619
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