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Acute pancreatitis

Ney, A; Pereira, SP; (2019) Acute pancreatitis. Medicine , 47 (4) pp. 241-249. 10.1016/j.mpmed.2019.01.007. Green open access

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Abstract

Acute pancreatitis is an inflammatory condition with a variable clinical course. Diagnosis is based on clinical presentation, laboratory studies and imaging. Disease severity is assessed using clinical scoring systems or radiological assessments such as the CT Severity Index. In most cases, the disease follows a mild course; however, a minority of cases are complicated by local and systemic complications. Management is usually conservative, while interventions are indicated where common bile duct stones or local complications, such as walled-off necrosis or pseudocyst formation, coexist. This review summarizes recent insights into the pathophysiology, investigation and treatment of acute pancreatitis, as well as common approaches to the management of local complications.

Type: Article
Title: Acute pancreatitis
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.mpmed.2019.01.007
Publisher version: https://doi.org/10.1016/j.mpmed.2019.01.007
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Acute pancreatitis; severity; antibiotics; nutrition; pseudocyst; endoscopic necrosectomy
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Inst for Liver and Digestive Hlth
URI: https://discovery.ucl.ac.uk/id/eprint/10081390
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