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Using Diffusion-Diffusion Exchange Spectroscopy to observe diffusion exchange in yeast

Breen-Norris, J; Siow, B; Hipwell, B; Roberts, T; Lythgoe, M; Ianus, A; Alexander, D; (2019) Using Diffusion-Diffusion Exchange Spectroscopy to observe diffusion exchange in yeast. Diffusion Fundamentals , 31 , Article 3. Green open access

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Abstract

The permeability of cell membranes varies significantly across both healthy and diseased tissue, and changes in cell membrane permeability can occur during treatment response in tumours. Measurements of cell membrane permeability could therefore be useful for tumour detection and as biomarkers of treatment response in the clinic. As the diffusion of water across the cell membrane is directly dependent on cell membrane permeability, we have investigated the ability of diffusion-diffusion exchange spectroscopy to quantify the diffusion exchange of water in a suspension of yeast, as a first step towards its application in tumours.

Type: Article
Title: Using Diffusion-Diffusion Exchange Spectroscopy to observe diffusion exchange in yeast
Open access status: An open access version is available from UCL Discovery
Publisher version: https://diffusion.uni-leipzig.de/contents_vol31.ph...
Language: English
Additional information: This work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
Keywords: DEXSY, diffusion exchange, permeability, double diffusion encoding, 2D-ILT.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Department of Imaging
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Experimental and Translational Medicine
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Computer Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/10081024
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