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What is a COPD-Like Spirometry Test Result in Resource Constrained Settings?

Gianella, GE; Miranda, JJ; Hurst, JR; (2019) What is a COPD-Like Spirometry Test Result in Resource Constrained Settings? COPD: Journal of Chronic Obstructive Pulmonary Disease , 16 (3-4) pp. 213-214. 10.1080/15412555.2019.1641794. Green open access

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Abstract

The diagnosis of chronic obstructive pulmonary disease (COPD), a global health problem, is challenging in resource-constrained settings. Spirometry with an obstructive pattern after the administration of bronchodilators is required for the diagnosis of COPD. Existing COPD treatment guidelines, largely derived from studies performed in populations of cigarette-smokers, recommend pharmacologic interventions with a tendency to include new-and expensive-drugs as first line agents. As the different factors that cause nonsmokers to develop COPD lead to different phenotypes of disease, COPD severity and treatment efficacy cannot be extrapolated to be the same as in the population of smokers. In so doing, current global initiatives may carry risks when trying to over simplify diagnostic approaches and push for standardization of treatment algorithms that are not context-specific. Future work to mitigate the global burden of COPD needs to address the need for new epidemiological data, especially in areas where tobacco use is less prevalent and environmental factors such as domestic air pollution is common.

Type: Article
Title: What is a COPD-Like Spirometry Test Result in Resource Constrained Settings?
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1080/15412555.2019.1641794
Publisher version: https://doi.org/10.1080/15412555.2019.1641794
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Chronic obstructive pulmonary disease, low and middle-income settings, spirometry test
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Respiratory Medicine
URI: https://discovery.ucl.ac.uk/id/eprint/10080636
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