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Composite Nano-fiber Mats Consisting of Biphasic Calcium Phosphate Loaded Polyvinyl Alcohol—Gelatin for Bone Tissue Engineering

Nguyen, LTB; Nguyen, TH; Huynh, CK; Lee, BT; Ye, H; (2019) Composite Nano-fiber Mats Consisting of Biphasic Calcium Phosphate Loaded Polyvinyl Alcohol—Gelatin for Bone Tissue Engineering. In: Proceedings of the International Conference on the Development of Biomedical Engineering in Vietnam. (pp. pp. 301-305). Springer Nature: Singapore. Green open access

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Abstract

Electrospun blends of biphasic calcium phosphate (BCP) loaded polyvinyl alcohol (PVA)-gelatin (GE) were created with the aim of fabricating biodegradable scaffolds for bone tissue engineering. The process parameters including the electrical field and tip-to-collector distance (TCD) were investigated. The morphology of these hybrid scaffolds were characterized by scanning electron microscope (SEM). X-ray diffraction (XRD) was used to determine the crystallinity of the membrane. Adhesion of osteoblastic cells (MG-63) onto the BCP loaded PVA/GE composite nano-fiber mat was performed to assess potential of the product as a bone scaffold. This result suggests that the BCP loaded PVA/GE composite nano-fiber mat has a high potential for use in the field of bone regeneration and tissue engineering.

Type: Proceedings paper
Title: Composite Nano-fiber Mats Consisting of Biphasic Calcium Phosphate Loaded Polyvinyl Alcohol—Gelatin for Bone Tissue Engineering
Event: 7th International Conference on the Development of Biomedical Engineering in Vietnam (BME7)
Location: Ho Chi Minh, Vietnam
Dates: 27th-29th Jun 2019
ISBN-13: 978-981-13-5858-6
Open access status: An open access version is available from UCL Discovery
DOI: 10.1007/978-981-13-5859-3_53
Publisher version: https://doi.org/10.1007/978-981-13-5859-3_53
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Electrospinning, Nano-fiber, Biphasic calcium phosphate nanoparticles, Bone tissue engineering
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Eastman Dental Institute
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Eastman Dental Institute > Biomaterials and Tissue Eng
URI: https://discovery.ucl.ac.uk/id/eprint/10080404
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