UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Looking to the future of zebrafish as a model to understand the genetic basis of eye disease

Cavodeassi, F; Wilson, SW; (2019) Looking to the future of zebrafish as a model to understand the genetic basis of eye disease. Human Genetics 10.1007/s00439-019-02055-z. (In press). Green open access

[img]
Preview
Text
Wilson_Looking to the future of zebrafish as a model to understand the genetic basis of eye disease_AOP.pdf - Published version

Download (558kB) | Preview

Abstract

In this brief commentary, we provide some of our thoughts and opinions on the current and future use of zebrafsh to model human eye disease, dissect pathological progression and advance in our understanding of the genetic bases of microphthalmia, andophthalmia and coloboma (MAC) in humans. We provide some background on eye formation in fsh and conservation and divergence across vertebrates in this process, discuss diferent approaches for manipulating gene function and speculate on future research areas where we think research using fsh may prove to be particularly efective.

Type: Article
Title: Looking to the future of zebrafish as a model to understand the genetic basis of eye disease
Location: Germany
Open access status: An open access version is available from UCL Discovery
DOI: 10.1007/s00439-019-02055-z
Publisher version: https://doi.org/10.1007/s00439-019-02055-z
Language: English
Additional information: This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Cell and Developmental Biology
URI: https://discovery.ucl.ac.uk/id/eprint/10080376
Downloads since deposit
24Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item