Cavodeassi, F;
Wilson, SW;
(2019)
Looking to the future of zebrafish as a model to understand the genetic basis of eye disease.
Human Genetics
10.1007/s00439-019-02055-z.
(In press).
Preview |
Text
Wilson_Looking to the future of zebrafish as a model to understand the genetic basis of eye disease_AOP.pdf - Published Version Download (558kB) | Preview |
Abstract
In this brief commentary, we provide some of our thoughts and opinions on the current and future use of zebrafsh to model human eye disease, dissect pathological progression and advance in our understanding of the genetic bases of microphthalmia, andophthalmia and coloboma (MAC) in humans. We provide some background on eye formation in fsh and conservation and divergence across vertebrates in this process, discuss diferent approaches for manipulating gene function and speculate on future research areas where we think research using fsh may prove to be particularly efective.
| Type: | Article |
|---|---|
| Title: | Looking to the future of zebrafish as a model to understand the genetic basis of eye disease |
| Location: | Germany |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1007/s00439-019-02055-z |
| Publisher version: | https://doi.org/10.1007/s00439-019-02055-z |
| Language: | English |
| Additional information: | This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Cell and Developmental Biology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10080376 |
Archive Staff Only
 |
View Item |
