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Intracorporeal lymph node mapping in colon cancer surgery

Soares, AS; Lovat, LB; Chand, M; (2019) Intracorporeal lymph node mapping in colon cancer surgery. EJSO - European Journal of Surgical Oncology 10.1016/j.ejso.2019.07.013. (In press). Green open access

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Abstract

INTRODUCTION: The best approach to lymphadenectomy in colon cancer is still unknown. The debate has centred around different options of standardised "one size fits all" lymph node harvest techniques. A different approach is tailoring lymph node harvest to the patient's lymphatic drainage pattern. // METHODS: A technique for individualised lymph node mapping is proposed, which can guide the surgeon intraoperatively. It consists in the intracorporeal injection of 10 mg of indocyanine green at 4 points in the periphery of the colonic tumour. A near infrared camera is used to assess the fluorescence after specimen mobilisation but before extraction, allowing lymphadenectomy based on the patient's own lymphatic drainage. // RESULTS: a video demonstration of the technique and preliminary results in 6 patients is presented in this short report. // CONCLUSION: intracorporeal lymph node mapping is feasible and safe. Further studies are required to determine the place of this technique in modern oncologic colon surgery.

Type: Article
Title: Intracorporeal lymph node mapping in colon cancer surgery
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.ejso.2019.07.013
Publisher version: https://doi.org/10.1016/j.ejso.2019.07.013
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Colon cancer, Fluorescence, Lymph node, Mapping
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Targeted Intervention
URI: https://discovery.ucl.ac.uk/id/eprint/10080333
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