UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Combined PET/MRI in brain glioma imaging

Almansory, KO; Fraioli, F; (2019) Combined PET/MRI in brain glioma imaging. British Journal of Hospital Medicine , 80 (7) pp. 380-386. 10.12968/hmed.2019.80.7.380. Green open access

[thumbnail of Fraioli_Combined PET MRI in brain glioma imaging_AAM.pdf]
Preview
Text
Fraioli_Combined PET MRI in brain glioma imaging_AAM.pdf - Accepted Version

Download (1MB) | Preview

Abstract

Gliomas are the most common primary brain tumours in children and adults, consisting of a heterogeneous group of neoplastic diseases arise from the supporting cells of the CNS (glial cells). Their histopathological and molecular characteristics vary considerably as do their management and prognosis. Conventional gadolinium-enhanced magnetic resonance imaging (MRI) is considered the primary imaging modality for initial work up and follow up of patients with gliomas, although it has some limitations, especially in differentiating high from low grade tumours and in distinguishing disease recurrence from post-therapy changes. Hybrid positron emission tomography (PET)/MRI is a relatively novel tool that combines MRI sequences with metabolic information from PET, and therefore different PET radiotracers, in a single scan. This article discusses the main advantages and disadvantages of combined PET/MRI compared to other conventional or more widely available imaging tools, such as MRI or combined positron emission tomography-computed tomography. The main uses of PET/MRI and the most commonly used PET radiotracers in providing diagnostic, prognostic and predictive information in patients with glioma are covered.

Type: Article
Title: Combined PET/MRI in brain glioma imaging
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.12968/hmed.2019.80.7.380
Publisher version: https://doi.org/10.12968/hmed.2019.80.7.380
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Department of Imaging
URI: https://discovery.ucl.ac.uk/id/eprint/10078948
Downloads since deposit
732Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item