UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Human Replay Spontaneously Reorganizes Experience

Liu, Y; Dolan, RJ; Kurth-Nelson, Z; Behrens, TEJ; (2019) Human Replay Spontaneously Reorganizes Experience. Cell 10.1016/j.cell.2019.06.012. (In press). Green open access

[img]
Preview
Text
1-s2.0-S0092867419306403-main.pdf - Published version

Download (6MB) | Preview

Abstract

Knowledge abstracted from previous experiences can be transferred to aid new learning. Here, we asked whether such abstract knowledge immediately guides the replay of new experiences. We first trained participants on a rule defining an ordering of objects and then presented a novel set of objects in a scrambled order. Across two studies, we observed that representations of these novel objects were reactivated during a subsequent rest. As in rodents, human "replay" events occurred in sequences accelerated in time, compared to actual experience, and reversed their direction after a reward. Notably, replay did not simply recapitulate visual experience, but followed instead a sequence implied by learned abstract knowledge. Furthermore, each replay contained more than sensory representations of the relevant objects. A sensory code of object representations was preceded 50 ms by a code factorized into sequence position and sequence identity. We argue that this factorized representation facilitates the generalization of a previously learned structure to new objects.

Type: Article
Title: Human Replay Spontaneously Reorganizes Experience
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.cell.2019.06.012
Publisher version: https://doi.org/10.1016/j.cell.2019.06.012
Language: English
Additional information: This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
Keywords: MEG, factorized representation, generalization, grid cells, hippocampus, inference, place cells, preplay, replay, transfer learning
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Imaging Neuroscience
URI: https://discovery.ucl.ac.uk/id/eprint/10078375
Downloads since deposit
0Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item