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Definition and treatment of arrhythmogenic cardiomyopathy: an updated expert panel report

Elliott, PM; Anastasakis, A; Asimaki, A; Basso, C; Bauce, B; Brooke, MA; Calkins, H; ... van Tintelen, JP; + view all (2019) Definition and treatment of arrhythmogenic cardiomyopathy: an updated expert panel report. European Journal of Heart Failure , 21 (8) pp. 955-964. 10.1002/ejhf.1534. Green open access

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Abstract

It is 35 years since the first description of arrhythmogenic right ventricular cardiomyopathy (ARVC) and more than 20 years since the first reports establishing desmosomal gene mutations as a major cause of the disease. Early advances in the understanding of the clinical, pathological and genetic architecture of ARVC resulted in consensus diagnostic criteria, which proved to be sensitive but not entirely specific for the disease. In more recent years, clinical and genetic data from families and the recognition of a much broader spectrum of structural disorders affecting both ventricles and associated with a propensity to ventricular arrhythmia have raised many questions about pathogenesis, disease terminology and clinical management. In this paper, we present the conclusions of an expert round table that aimed to summarise the current state of the art in arrhythmogenic cardiomyopathies and to define future research priorities.

Type: Article
Title: Definition and treatment of arrhythmogenic cardiomyopathy: an updated expert panel report
Open access status: An open access version is available from UCL Discovery
DOI: 10.1002/ejhf.1534
Publisher version: https://doi.org/10.1002/ejhf.1534
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Arrhythmogenic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Ventricular arrhythmias
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Clinical Science
URI: https://discovery.ucl.ac.uk/id/eprint/10077182
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