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Stratifying management of rheumatic disease for pregnancy and breastfeeding

Giles, I; Yee, C-S; Gordon, C; (2019) Stratifying management of rheumatic disease for pregnancy and breastfeeding. Nature Reviews Rheumatology , 15 pp. 391-402. 10.1038/s41584-019-0240-8. Green open access

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Abstract

The management of inflammatory rheumatic diseases during pregnancy and breastfeeding has undergone considerable change in the past few years. Modern therapeutics, including biologic and targeted synthetic DMARDs, have enabled substantial improvements in the control of rheumatic diseases, resulting in more patients with severe disease considering pregnancy. Therefore, management of disease for these patients needs to be discussed with clinicians before, during and after pregnancy and patients need to know what complications they might experience before they become pregnant. This Review summarizes the effects pregnancy has on various rheumatic diseases and the effects these diseases have on pregnancy, as well as providing advice regarding the alteration and monitoring of therapy before, during and after pregnancy.

Type: Article
Title: Stratifying management of rheumatic disease for pregnancy and breastfeeding
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1038/s41584-019-0240-8
Publisher version: https://doi.org/10.1038/s41584-019-0240-8
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Inflammation
URI: https://discovery.ucl.ac.uk/id/eprint/10076870
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