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Mentalization-Based Treatment Versus Specialist Treatment as Usual for Borderline Personality Disorder: Economic Evaluation Alongside a Randomized Controlled Trial With 36-Month Follow-Up

Blankers, M; Koppers, D; Laurenssen, EMP; Peen, J; Smits, ML; Luyten, P; Busschbach, J; ... Dekker, J; + view all (2020) Mentalization-Based Treatment Versus Specialist Treatment as Usual for Borderline Personality Disorder: Economic Evaluation Alongside a Randomized Controlled Trial With 36-Month Follow-Up. Journal of Personality Disorders 10.1521/pedi_2019_33_454. (In press).

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Luyten 190614-Economic evaluation MBT-DH vs S-TAU-na-peer-review-1-clean.pdf - Accepted version
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Luyten 190614-Economic evaluation MBT-DH vs S-TAU-supplements-JPD.pdf - Accepted version
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2019-06-14Figure-1-MBT-CEA.pdf - Accepted version
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Abstract

This paper presents an economic evaluation performed alongside a randomized controlled trial of Mentalization-Based Treatment in a Day Hospital setting (MBT-DH) versus specialist treatment as usual (S-TAU) for borderline personality disorder (BPD) with a 36-month follow-up period. Ninety-five patients from two Dutch treatment institutes were randomly assigned. Societal costs were compared with the proportion of BPD remissions and quality-adjusted life years (QALYs) measured using the five-dimensional EuroQol instrument. The incremental societal costs for one additional QALY could not be calculated. The costs for one additional BPD remission with MBT-DH are approximately €29,000. There was a 58% likelihood that MBT-DH leads to more remitted patients at additional costs compared with S-TAU, and a 35% likelihood that MBT-DH leads to more remissions at lower costs. MBT-DH is not cost-effective compared with S-TAU with QALYs as the outcome, and slightly more cost-effective than S-TAU at 36 months with BPD symptoms as the outcome.

Type: Article
Title: Mentalization-Based Treatment Versus Specialist Treatment as Usual for Borderline Personality Disorder: Economic Evaluation Alongside a Randomized Controlled Trial With 36-Month Follow-Up
DOI: 10.1521/pedi_2019_33_454
Publisher version: https://doi.org/10.1521/pedi_2019_33_454
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Economic evaluation, Mentalization-based treatment, Borderline personality disorder, Randomized controlled trial
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences > Clinical, Edu and Hlth Psychology
URI: https://discovery.ucl.ac.uk/id/eprint/10076867
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