UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Neural tissue engineering with structured hydrogels in CNS models and therapies

George, J; Hsu, CC; Nguyen, LTB; Ye, H; Cui, Z; (2019) Neural tissue engineering with structured hydrogels in CNS models and therapies. Biotechnology Advances 10.1016/j.biotechadv.2019.03.009. Green open access

[img]
Preview
Text
George_AIP_1-s2.0-S073497501930045X-main.pdf - Published version

Download (2MB) | Preview

Abstract

The development of techniques to create and use multiphase microstructured hydrogels (granular hydrogels or microgels) has enabled the generation of cultures with more biologically relevant architecture and use of structured hydrogels is especially pertinent to the development of new types of central nervous system (CNS) culture models and therapies. We review material choice and the customisation of hydrogel structure, as well as the use of hydrogels in developmental models. Combining the use of structured hydrogel techniques with developmentally relevant tissue culture approaches will enable the generation of more relevant models and treatments to repair damaged CNS tissue architecture.

Type: Article
Title: Neural tissue engineering with structured hydrogels in CNS models and therapies
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.biotechadv.2019.03.009
Publisher version: https://doi.org/10.1016/j.biotechadv.2019.03.009
Language: English
Additional information: © 2019 Elsevier Inc. Open Access. Licensed under the terms of the Creative Commons Attribution 4.0 International (CC BY 4.0) Licence (https://creativecommons.org/licenses/ by/4.0/).
Keywords: Extracellular matrix, Neuron, Structured Hydrogel, Microgel, Granular hydrogel, Tissue Engineering, Regenerative Medicine
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Eastman Dental Institute
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Eastman Dental Institute > Biomaterials and Tissue Eng
URI: https://discovery.ucl.ac.uk/id/eprint/10076637
Downloads since deposit
132Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item